cpu-architecture
Mentors and Regional Facilitators
| Name | Region | Skills | Interests |
|---|---|---|---|
| Adam Carlson | Campus Champions | ||
| Charles Forsyth | Campus Champions | ||
| Cody Stevens | Campus Champions, CCMNet | ||
| Chris Reidy | Campus Champions, CCMNet | ||
| Daniel Benedict | CCMNet | ||
| Deborah Penchoff | Campus Champions | ||
| Elizabeth Leake | CCMNet | ||
| Jeff Falgout | Campus Champions, RMACC | ||
| Julie Ma | ACCESS CSSN, At-Large, Campus Champions, CAREERS, CCMNet, Northeast | ||
| James Hutcheson | Campus Champions, ACCESS CSSN | ||
| Michael Schnaitter | ACCESS CSSN | ||
| Ron Rahaman | Campus Champions | ||
| Ruben Lara | Campus Champions | ||
| Liwen Shih | Campus Champions, ACCESS CSSN, CCMNet | ||
| Steven Kuhlo | TRECIS | ||
| Thomas Pranzatelli | |||
| Trey Breckenridge | Campus Champions |
Affinity Groups
There are no Affinity Groups associated with this topic. View All Affinity Groups.
Announcements
There are no announcements with this tag. View All Announcements.
Upcoming Events & Trainings
Topics from Ask.CI
Loading topics from Ask.CI ...
Knowledge Base Resources
| Title | Category | Tags | Skill Level |
|---|---|---|---|
| Building the ArduPilot environment for Linux | Docs | profiling, data-transfer, github, github-pages, cpu-architecture, bash, environment-modules, git, modules, os, permissions, ssh, vim | Beginner |
| CI Computing Module For All | Learning | ai, computer-vision, neural-networks, visualization, big-data, gis, parallelization, data-management, data-science, bioinformatics, open-ondemand, hpc-getting-started, cpu-architecture, distributed-computing, job-submission, jupyterhub, python, r, cybersecurity, containers | Beginner |
Engagements
Re-engineering Lilly’s KisunlaTM into a novel antibody targeting IL13RA2 against GBM using AI-driven macromolecular modeling
Atrium Health Levine Cancer
- Summary and objectives of the proposed experiments:
- An initial research-based Ab (scFv47, discovered by our collaborator Dr. Balyasnikova) model, modeling Ab-Ag (IL13RA2 against GBM) protein complex, and identifying the binding sites (epitopes) using ROSETTA and AlphaFold2 multimer tools.
- Graft the CDRs of scFv (single-chain variable fragment) of antibody or Bispecific T cell engagers (BTEs) onto the template Ab, the framework of Lilly's Kisunla™ Ab drug.
- Modify, improve, and optimize the overall or full antibody protein structures using AI-driven macromolecule modeling (AlphaFold3).
- Explore single nucleotide polymorphism (SNP), pathogenic genetic variants and N-glycosylation of IL13RA2 (target) protein domain interacting with the Ab candidates among the patient population using ROSETTA software packages.
Status: In Progress
People with Expertise
Elizabeth Leake
Texas A&M University
Programs
CCMNet
Roles
mentor, research computing facilitator, CCMNet
Expertise
Michael Schnaitter
Programs
ACCESS CSSN
Roles
research computing facilitator, ci systems engineer, cssn
Expertise
Trey Breckenridge
Mississippi State University
Programs
Campus Champions
Roles
research computing facilitator
Expertise
People with Interest
Tajendra Vir Singh
University of California, Los Angeles
Programs
Campus Champions
Roles
research computing facilitator
Interests
Dr. Nabeel Alzahrani
California State University-San Bernardino
Programs
Campus Champions, CCMNet
Roles
mentor, researcher/educator, research computing facilitator, research software engineer, ci systems engineer, CCMNet
Interests
Wirawan Purwanto
Old Dominion University
Programs
Campus Champions, Northeast, ACCESS CSSN
Roles
mentor, research computing facilitator, cssn