deployment
Mentors and Regional Facilitators
| Name | Region | Skills | Interests |
|---|---|---|---|
| Michael Blackmon | Campus Champions, ACCESS CSSN | ||
| Brian Haymore | Campus Champions, RMACC, CCMNet | ||
| Charles Forsyth | Campus Champions | ||
| Cody Stevens | Campus Champions, CCMNet | ||
| Daniel Benedict | CCMNet | ||
| Edwin Posada | Campus Champions | ||
| Jeff Falgout | Campus Champions, RMACC | ||
| Jack Garmer | Campus Champions | ||
| Michael Schnaitter | ACCESS CSSN | ||
| Ric Anderson | Campus Champions | ||
| Sumit Saluja | Campus Champions | ||
| Timothy Middelkoop | ACCESS CSSN, Campus Champions, CCMNet, Great Plains |
Affinity Groups
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Upcoming Events & Trainings
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Knowledge Base Resources
| Title | Category | Tags | Skill Level |
|---|---|---|---|
| Containerized Jupyter Notebooks for HPCs | Learning | cloud, cloud-computing, openstack, scratch, data-management, data-reproducibility, github, workflow, open-ondemand, administering-hpc, configuration-automation, hpc-getting-started, hpc-tools, deployment, scripting, conda, jupyterhub, programming-best-practices, python, mpi, containers, docker, singularity | Intermediate |
Engagements
Re-engineering Lilly’s KisunlaTM into a novel antibody targeting IL13RA2 against GBM using AI-driven macromolecular modeling
Atrium Health Levine Cancer
- Summary and objectives of the proposed experiments:
- An initial research-based Ab (scFv47, discovered by our collaborator Dr. Balyasnikova) model, modeling Ab-Ag (IL13RA2 against GBM) protein complex, and identifying the binding sites (epitopes) using ROSETTA and AlphaFold2 multimer tools.
- Graft the CDRs of scFv (single-chain variable fragment) of antibody or Bispecific T cell engagers (BTEs) onto the template Ab, the framework of Lilly's Kisunla™ Ab drug.
- Modify, improve, and optimize the overall or full antibody protein structures using AI-driven macromolecule modeling (AlphaFold3).
- Explore single nucleotide polymorphism (SNP), pathogenic genetic variants and N-glycosylation of IL13RA2 (target) protein domain interacting with the Ab candidates among the patient population using ROSETTA software packages.
Status: In Progress
People with Expertise
Michael Schnaitter
Programs
ACCESS CSSN
Roles
research computing facilitator, ci systems engineer, cssn
Expertise
Expertise
Expertise
People with Interest
Matthew Chung
University of California, Riverside
Programs
ACCESS CSSN, CCMNet
Roles
research computing facilitator, ci systems engineer, cssn, CCMNet
Interests
Timothy Middelkoop
Internet2
Programs
ACCESS CSSN, Campus Champions, CCMNet, Great Plains
Roles
mentor, regional facilitator, researcher/educator, research computing facilitator, CCMNet
Interests
Manas Vishal
University of Massachusetts, Dartmouth
Programs
CAREERS, Northeast, CCMNet
Roles
student-facilitator, CCMNet